Name | Drotaverin hydrochloride |
Synonyms | DROTAVERINE DROTAVERINE HCL Drotaverin hydrochloride drotaverin hydrochloride isodihydroperparine hydrochloride 6,7,3',4'-tetraethoxy-1-benzal-1,2,3,4-tetrahydroisoquinoline hydrochloride 1-[(3,4-DIETHOXYPHENYL)METHYLENE]-6,7-DIETHOXY 1,2,3,4-TETRAHYDROISOQUINOLINE HCL 1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride (1z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-3,4-dihydro-2h-isoquinoline hydrochloride |
CAS | 14009-24-6 |
EINECS | 604-171-8 |
Molecular Formula | C24H31NO4 |
Molar Mass | 397.51 |
Density | 1.1507 (rough estimate) |
Boling Point | 520.94°C (rough estimate) |
Water Solubility | 13.75g/L(37 ºC) |
pKa | 6.17±0.20(Predicted) |
Refractive Index | 1.6000 (estimate) |
antispasmodic drugs | There are two kinds of tablet and injection of dritaviline hydrochloride, each needle (2ml) and 40mg of Drotaverine hydrochloride per tablet, acting directly on visceral smooth muscle and used to relieve or prevent the onset of various types of smooth muscle spasms, whether functional or neurotic. Its antispasmodic effect is many times stronger than the same role in smooth muscle papaverine, and the duration is long, this product only acts on smooth muscle and does not affect the autonomic nervous system, so it is used as anti-biliary antispasmodic drugs. Suitable for gastrointestinal spasm, biliary colic such as cholecystitis, gallstones, renal colic such as kidney stones, ureteral calculi, pyelonephritis, cystitis, dysmenorrhea, etc. |
Main use and usage | treatment of gastrointestinal spastic pain, gallbladder, renal colic and dysmenorrhea. Oral, 40~80mg,tid; Children under 6 years of age 20~40mg,tid, more than 6 years of age 40mg,tid. Can also be subcutaneous injection or intramuscular injection, 40~80mg; If necessary, 6~8 hours after repeated injection. If the pain does not relieve, can also be used 40~80mg slow intravenous injection. |
adverse reactions and precautions | Nausea, palpitation, Head Pain, dizziness and hypotension, etc. Glaucoma, allergy to this drug, porphyria, prostatic hyperplasia, severe heart, liver, renal insufficiency patients were prohibited. Avoid taking during pregnancy and lactation unless necessary. |